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Enhanced memory responses to H1N1 influenza vaccination in the skin using vaccine coated-microneedles
BACKGROUND: Morbidity and mortality due to influenza could be reduced by improved vaccination. METHODS: To develop a novel skin delivery method for simple and self administration, we prepared microneedle patches with stabilized influenza vaccine and investigated their protective immune responses. RE...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2010
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798016/ https://ncbi.nlm.nih.gov/pubmed/20017632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/649228 |
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