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Low Muscle Glycogen and Elevated Plasma Free Fatty Acid Modify but Do Not Prevent Exercise-Induced PDH Activation in Human Skeletal Muscle

OBJECTIVE: To test the hypothesis that free fatty acid (FFA) and muscle glycogen modify exercise-induced regulation of PDH (pyruvate dehydrogenase) in human skeletal muscle through regulation of PDK4 expression. RESEARCH DESIGN AND METHODS: On two occasions, healthy male subjects lowered (by exercis...

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Autors principals: Kiilerich, Kristian, Gudmundsson, Mikkel, Birk, Jesper B., Lundby, Carsten, Taudorf, Sarah, Plomgaard, Peter, Saltin, Bengt, Pedersen, Per A., Wojtaszewski, Jorgen F.P., Pilegaard, Henriette
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797931/
https://ncbi.nlm.nih.gov/pubmed/19833896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1032
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