Direct rosiglitazone action on steroidogenesis and proinflammatory factor production in human granulosa-lutein cells

BACKGROUND: Ovarian granulosa cells are the predominant source of estradiol and progesterone biosynthesis in vivo. Rosiglitazone, a synthetic agonist of the peroxisome proliferator-activated receptor gamma (PPAR gamma), is applied as the treatment of insulin resistance including women with PCOS. The...

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Autors principals: Chen, Qiuju, Sun, Xiaoxi, Chen, Junling, Cheng, Linan, Wang, Jian, Wang, Yongwei, Sun, Zhaogui
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797791/
https://ncbi.nlm.nih.gov/pubmed/20003221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-7-147
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