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Structural and Functional Roles of Coevolved Sites in Proteins

BACKGROUND: Understanding the residue covariations between multiple positions in protein families is very crucial and can be helpful for designing protein engineering experiments. These simultaneous changes or residue coevolution allow protein to maintain its overall structural-functional integrity...

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Detalhes bibliográficos
Main Authors: Chakrabarti, Saikat, Panchenko, Anna R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797611/
https://ncbi.nlm.nih.gov/pubmed/20066038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008591
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