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Prediction of functional sites by analysis of sequence and structure conservation
We present a method for prediction of functional sites in a set of aligned protein sequences. The method selects sites which are both well conserved and clustered together in space, as inferred from the 3D structures of proteins included in the alignment. We tested the method using 86 alignments fro...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2280064/ https://ncbi.nlm.nih.gov/pubmed/15010543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03465504 |
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