Kidney Development in the Absence of Gdnf and Spry1 Requires Fgf10

GDNF signaling through the Ret receptor tyrosine kinase (RTK) is required for ureteric bud (UB) branching morphogenesis during kidney development in mice and humans. Furthermore, many other mutant genes that cause renal agenesis exert their effects via the GDNF/RET pathway. Therefore, RET signaling...

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Detalhes bibliográficos
Main Authors: Michos, Odyssé, Cebrian, Cristina, Hyink, Deborah, Grieshammer, Uta, Williams, Linda, D'Agati, Vivette, Licht, Jonathan D., Martin, Gail R., Costantini, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797609/
https://ncbi.nlm.nih.gov/pubmed/20084103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000809
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