Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.
Whole-cell and single-channel recording techniques were used to study the action of the anticonvulsant drug MK-801 [(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]- cyclohepten-5,10-imine maleate) on responses to excitatory amino acids in rat neocortical neurons in cell culture. MK-801 caused a progressi...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1988
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2448800/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.4.1307 |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|