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Biochemical Techniques for the Characterization of G-Quadruplex Structures: EMSA, DMS Footprinting, and DNA Polymerase Stop Assay

The proximal promoter region of many human growth-related genes contains a polypurine/polypyrimidine tract that serves as a multiple binding site for Sp1 or other transcription factors. These tracts often contain a guanine-rich sequence consisting of four runs of three or more contiguous guanines se...

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Detalhes bibliográficos
Main Authors: Sun, Daekyu, Hurley, Laurence H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797547/
https://ncbi.nlm.nih.gov/pubmed/20012416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-363-9_5
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