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cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor.

Nerve growth factor (NGF) is a neurotrophic agent for sympathetic and embryonic sensory neurons both in vivo and in vitro. We report here that the membrane-permeant cAMP analogs, 8-(4-chlorophenylthio)-cAMP and 8-bromo-cAMP, can replace NGF in promoting long-term survival and neurite outgrowth in cu...

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Bibliografski detalji
Glavni autori: Rydel, R E, Greene, L A
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC279746/
https://ncbi.nlm.nih.gov/pubmed/2829221
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