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Structure of the hDmc1-ssDNA Filament Reveals the Principles of Its Architecture
In eukaryotes, meiotic recombination is a major source of genetic diversity, but its defects in humans lead to abnormalities such as Down's, Klinefelter's and other syndromes. Human Dmc1 (hDmc1), a RecA/Rad51 homologue, is a recombinase that plays a crucial role in faithful chromosome segr...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797393/ https://ncbi.nlm.nih.gov/pubmed/20062530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008586 |
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