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Single Vesicle Millisecond Fusion Kinetics Reveals Number of SNARE Complexes Optimal for Fast SNARE-mediated Membrane Fusion

SNAREs mediate membrane fusion in intracellular vesicle traffic and neuronal exocytosis. Reconstitution of membrane fusion in vitro proved that SNAREs constitute the minimal fusion machinery. However, the slow fusion rates observed in these systems are incompatible with those required in neurotransm...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Domanska, Marta K., Kiessling, Volker, Stein, Alexander, Fasshauer, Dirk, Tamm, Lukas K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797286/
https://ncbi.nlm.nih.gov/pubmed/19759010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047381
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