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Single Vesicle Millisecond Fusion Kinetics Reveals Number of SNARE Complexes Optimal for Fast SNARE-mediated Membrane Fusion

SNAREs mediate membrane fusion in intracellular vesicle traffic and neuronal exocytosis. Reconstitution of membrane fusion in vitro proved that SNAREs constitute the minimal fusion machinery. However, the slow fusion rates observed in these systems are incompatible with those required in neurotransm...

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Detalhes bibliográficos
Main Authors: Domanska, Marta K., Kiessling, Volker, Stein, Alexander, Fasshauer, Dirk, Tamm, Lukas K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797286/
https://ncbi.nlm.nih.gov/pubmed/19759010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047381
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