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Structural Basis for Phototoxicity of the Genetically Encoded Photosensitizer KillerRed

KillerRed is the only known fluorescent protein that demonstrates notable phototoxicity, exceeding that of the other green and red fluorescent proteins by at least 1,000-fold. KillerRed could serve as an instrument to inactivate target proteins or to kill cell populations in photodynamic therapy. Ho...

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Main Authors: Pletnev, Sergei, Gurskaya, Nadya G., Pletneva, Nadya V., Lukyanov, Konstantin A., Chudakov, Dmitri M., Martynov, Vladimir I., Popov, Vladimir O., Kovalchuk, Mikhail V., Wlodawer, Alexander, Dauter, Zbigniew, Pletnev, Vladimir
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797274/
https://ncbi.nlm.nih.gov/pubmed/19737938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.054973
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