High Resolution NMR-based Model for the Structure of a scFv-IL-1β Complex: POTENTIAL FOR NMR AS A KEY TOOL IN THERAPEUTIC ANTIBODY DESIGN AND DEVELOPMENT

Monoclonal antibodies have recently started to deliver on their promise as highly specific and active drugs; however, a more effective, knowledge-based approach to the selection, design, and optimization of potential therapeutic antibodies is currently limited by the surprising lack of detailed stru...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Wilkinson, Ian C., Hall, Catherine J., Veverka, Vaclav, Shi, Jiye Y., Muskett, Frederick W., Stephens, Paul E., Taylor, Richard J., Henry, Alistair J., Carr, Mark D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797264/
https://ncbi.nlm.nih.gov/pubmed/19776018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.025304
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars