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Homocysteine Supplementation Attenuates the Unfolded Protein Response in a Murine Nutritional Model of Steatohepatitis

Hyperhomocysteinemia has been correlated with hepatic steatosis and activation of the unfolded protein response (UPR), yet a causal relationship has not been established. Although methionine and choline are essential components of homocysteine metabolism, the role of homocysteine in the pathogenesis...

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Sonraí Bibleagrafaíochta
Main Authors: Henkel, Anne S., Elias, Marc S., Green, Richard M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797251/
https://ncbi.nlm.nih.gov/pubmed/19762918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017970
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