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Non-classical Natural Killer T Cells Modulate Plasmid DNA Vaccine Antigen Expression and Vaccine-elicited Immune Responses by MCP-1 Secretion after Interaction with a β2-Microglobulin-independent CD1d

The magnitude and durability of a plasmid DNA vaccine-induced immune response is shaped by immune effector molecules at the site of vaccination. In the present study, we show that antigen expression is modified by type II NKT cells, after interaction with a β2-microglobulin-independent CD1d receptor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Geiben-Lynn, Ralf, Greenland, John R., Frimpong-Boateng, Kwesi, Letvin, Norman L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797149/
https://ncbi.nlm.nih.gov/pubmed/19833737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019638
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