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Disruption of occludin function in polarized epithelial cells activates the extrinsic pathway of apoptosis leading to cell extrusion without loss of transepithelial resistance

BACKGROUND: Occludin is a tetraspanin protein normally localized to tight junctions. The protein interacts with a variety of pathogens including viruses and bacteria, an interaction that sometimes leads to its extrajunctional localization. RESULTS: Here we report that treatment of mammary epithelial...

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Main Authors: Beeman, Neal E, Baumgartner, Heidi K, Webb, Patricia G, Schaack, Jerome B, Neville, Margaret C
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796999/
https://ncbi.nlm.nih.gov/pubmed/20003227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-10-85
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