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Effects of cocaine self-administration history under limited and extended access conditions on in vivo striatal dopamine neurochemistry and acoustic startle in rhesus monkeys

RATIONALE: The transition from infrequent and controlled cocaine use to dependence may involve enduring changes in neurobiology as a consequence of persistent drug use. OBJECTIVE: The present study utilized an intravenous drug self-administration protocol of increasing cocaine access to evaluate pot...

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Détails bibliographiques
Auteurs principaux: Henry, Porche’ Kirkland, Davis, Michael, Howell, Leonard L.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796974/
https://ncbi.nlm.nih.gov/pubmed/19365621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-009-1534-3
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