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Evidence for a role of vertebrate Disp1 in long-range Shh signaling
Dispatched 1 (Disp1) encodes a twelve transmembrane domain protein that is required for long-range sonic hedgehog (Shh) signaling. Inhibition of Disp1 function, both by RNAi or dominant-negative constructs, prevents secretion and results in the accumulation of Shh in source cells. Measuring the Shh...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Company of Biologists
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796928/ https://ncbi.nlm.nih.gov/pubmed/20023168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.043547 |
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