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Correcting “winner's curse” in odds ratios from genomewide association findings for major complex human diseases
Genome-wide association studies (GWAS) provide an important approach for identifying common genetic variants that predispose to human disease. However, odds ratio (OR) estimates for the reported findings from GWAS discovery data are typically affected by a bias away from the null sometimes referred...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796696/ https://ncbi.nlm.nih.gov/pubmed/19639606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20437 |
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