Targeting the Epidermal Growth Factor Receptor in Epithelial Ovarian Cancer: Current Knowledge and Future Challenges

The epidermal growth factor receptor is overexpressed in up to 60% of ovarian epithelial malignancies. EGFR regulates complex cellular events due to the large number of ligands, dimerization partners, and diverse signaling pathways engaged. In ovarian cancer, EGFR activation is associated with incre...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Siwak, Doris R., Carey, Mark, Hennessy, Bryan T., Nguyen, Catherine T., McGahren Murray, Mollianne J., Nolden, Laura, Mills, Gordon B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Hindawi Publishing Corporation 2010
विषय:
Review Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796463/
https://ncbi.nlm.nih.gov/pubmed/20037743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/568938
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