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Tbx1 regulates proliferation and differentiation of multipotent heart progenitors

RATIONALE: TBX1 encodes a T-box transcription factor implicated in DiGeorge syndrome, which affects the development of many organs, including the heart. Loss of Tbx1 results into hypoplasia of heart regions derived from the second heart field (SHF), a population of cardiac progenitors cells (CPCs)....

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Hlavní autoři: Chen, Li, Fulcoli, Filomena Gabriella, Tang, Susan, Baldini, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796444/
https://ncbi.nlm.nih.gov/pubmed/19745164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.200295
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