The Yeast Iron Regulatory Proteins Grx3/4 and Fra2 Form Heterodimeric Complexes Containing a [2Fe-2S] Cluster with Cysteinyl and Histidyl Ligation

The transcription of iron uptake and storage genes in S. cerevisiae is primarily regulated by the transcription factor Aft1. Nucleocytoplasmic shuttling of Aft1 is dependent upon mitochondrial Fe-S cluster biosynthesis via a signaling pathway that includes the cytosolic monothiol glutaredoxins (Grx3...

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Hauptverfasser: Li, Haoran, Mapolelo, Daphne T., Dingra, Nin N., Naik, Sunil G., Lees, Nicolas S., Hoffman, Brian M., Riggs-Gelasco, Pamela J., Huynh, Boi Hanh, Johnson, Michael K., Outten, Caryn E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796373/
https://ncbi.nlm.nih.gov/pubmed/19715344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901182w
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