Gin-mediated DNA inversion: product structure and the mechanism of strand exchange.

Inversion of the G loop of bacteriophage Mu requires the phage-encoded Gin protein and a host factor. The topological changes in a supercoiled DNA substrate generated by the two purified proteins were analyzed. More than 99% of the inversion products were unknotted rings. This result excludes synaps...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kanaar, R, van de Putte, P, Cozzarelli, N R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279633/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829201/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.3.752
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