Gin-mediated DNA inversion: product structure and the mechanism of strand exchange.

Inversion of the G loop of bacteriophage Mu requires the phage-encoded Gin protein and a host factor. The topological changes in a supercoiled DNA substrate generated by the two purified proteins were analyzed. More than 99% of the inversion products were unknotted rings. This result excludes synaps...

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Bibliographic Details
Main Authors: Kanaar, R, van de Putte, P, Cozzarelli, N R
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC279633/
https://ncbi.nlm.nih.gov/pubmed/2829201
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