Structural Basis of Chemokine Sequestration by a Tick Chemokine Binding Protein: The Crystal Structure of the Complex between Evasin-1 and CCL3

BACKGROUND: Chemokines are a subset of cytokines responsible for controlling the cellular migration of inflammatory cells through interaction with seven transmembrane G protein-coupled receptors. The blocking of a chemokine-receptor interaction results in a reduced inflammatory response, and represe...

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Main Authors: Dias, João M., Losberger, Christophe, Déruaz, Maud, Power, Christine A., Proudfoot, Amanda E. I., Shaw, Jeffrey P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796168/
https://ncbi.nlm.nih.gov/pubmed/20041127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008514
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