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Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice

Type 1 von Willebrand disease (VWD) is the most common inherited human bleeding disorder. However, diagnosis is complicated by incomplete penetrance and variable expressivity, as well as wide variation in von Willebrand factor (VWF) levels among the normal population. Previous work has exploited the...

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Détails bibliographiques
Auteurs principaux: Shavit, Jordan A., Manichaikul, Ani, Lemmerhirt, Heidi L., Broman, Karl W., Ginsburg, David
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796139/
https://ncbi.nlm.nih.gov/pubmed/19789385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-233213
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