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Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice

Type 1 von Willebrand disease (VWD) is the most common inherited human bleeding disorder. However, diagnosis is complicated by incomplete penetrance and variable expressivity, as well as wide variation in von Willebrand factor (VWF) levels among the normal population. Previous work has exploited the...

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Autors principals: Shavit, Jordan A., Manichaikul, Ani, Lemmerhirt, Heidi L., Broman, Karl W., Ginsburg, David
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796139/
https://ncbi.nlm.nih.gov/pubmed/19789385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-233213
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