Synergy between tumor necrosis factor and bacterial products causes hemorrhagic necrosis and lethal shock in normal mice.
We find a strong synergism between tumor necrosis factor (TNF) and bacteria or their products. Endotoxin-"free" recombinant TNF, even at very high doses (160 micrograms), did not alone cause hemorrhagic necrosis (HN) in the skin of normal mice. Similarly, TNF alone had a low systemic toxicity in tum...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
1988
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3422444/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.2.607 |
| Tagit: |
Ei tageja, Lisää ensimmäinen tagi!
|