Integration of gene ontology pathways with North American Rheumatoid Arthritis Consortium genome-wide association data via linear modeling

We describe an empirical Bayesian linear model for integration of functional gene annotation data with genome-wide association data. Using case-control study data from the North American Rheumatoid Arthritis Consortium and gene annotation data from the Gene Ontology, we illustrate how the method can...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lebrec, Jérémie JP, Huizinga, Tom WJ, Toes, René EM, Houwing-Duistermaat, Jeanine J, van Houwelingen, Hans C
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2009
Sujets:
Proceedings
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795998/
https://ncbi.nlm.nih.gov/pubmed/20018091
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