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The effect of minor allele frequency on the likelihood of obtaining false positives
Determining the most promising single-nucleotide polymorphisms (SNPs) presents a challenge in genome-wide association studies, when hundreds of thousands of association tests are conducted. The power to detect genetic effects is dependent on minor allele frequency (MAF), and genome-wide association...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795940/ https://ncbi.nlm.nih.gov/pubmed/20018033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-3-S7-S41 |
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