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A method to correct for population structure using a segregation model

To overcome the "spurious" association caused by population stratification in population-based association studies, we propose a principal-component based method that can use both family and unrelated samples at the same time. More specifically, we adapt the multivariate logistic model, wh...

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Detalhes bibliográficos
Main Authors: Feng, Qingfu, Abraham, Joseph, Feng, Tao, Song, Yeunjoo, Elston, Robert C, Zhu, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795875/
https://ncbi.nlm.nih.gov/pubmed/20017968
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