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Loss of PKD1 and loss of Bcl-2 elicit polycystic kidney disease through distinct mechanisms
We have recently demonstrated that ablation of one or both alleles of the proapoptotic gene Bim prevents the polycystic kidney disease (PKD) that develops in mice deficient for the prosurvival protein Bcl-2. The aim of the present study was to investigate whether loss of Bim or Bcl-2 could influence...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795698/ https://ncbi.nlm.nih.gov/pubmed/16282979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.cdd.4401815 |
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