Expression, purification and preliminary X-ray analysis of proliferating cell nuclear antigen from the archaeon Thermococcus thioreducens

Proliferating cell nuclear antigen (PCNA) is a DNA sliding clamp which confers processivity on replicative DNA polymerases. PCNA also acts as a sliding platform that enables the association of many DNA-processing proteins with DNA in a non-sequence-specific manner. In this investigation, the PCNA fr...

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Bibliographic Details
Main Authors: Byrne-Steele, Miranda L., Ng, Joseph D.
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2009
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795597/
https://ncbi.nlm.nih.gov/pubmed/19724129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910903036X
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