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Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repair

The evolutionarily conserved Smc5/6 complex is implicated in recombinational repair, but its function in this process has been elusive. Here we report that the budding yeast Smc5/6 complex directly binds to the DNA helicase Mph1. Mph1 and its helicase activity define a replication-associated recombi...

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Detalhes bibliográficos
Main Authors: Chen, Yu-Hung, Choi, Koyi, Szakal, Barnabas, Arenz, Jacqueline, Duan, Xinyuan, Ye, Hong, Branzei, Dana, Zhao, Xiaolan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795505/
https://ncbi.nlm.nih.gov/pubmed/19995966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908258106
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