Carboxyl-terminal mutants of the large tumor antigen of simian virus 40: a role for the early protein late in the lytic cycle.

Simian virus 40 (SV40) mutants dl1066 and dl1140 contain deletions within the region encoding the carboxyl terminus of the large tumor (T) antigen. Although these mutations have little effect on the efficiency of viral DNA replication, they decrease the yield of infectious virus particles by 3-4 ord...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Khalili, K, Brady, J, Pipas, J M, Spence, S L, Sadofsky, M, Khoury, G
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1988
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2829182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.2.354
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