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Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant.

We have used the multifunctional transforming protein, simian virus 40 T antigen, as a probe to study the mechanisms of cell growth regulation in the intact organism. T antigen appears to perturb cell growth, at least in part, by stably interacting with specific cellular proteins that function to ma...

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Detalles Bibliográficos
Autores principales: Symonds, H S, McCarthy, S A, Chen, J, Pipas, J M, Van Dyke, T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC359774/
https://ncbi.nlm.nih.gov/pubmed/8388535
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