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The ratio of maximum percent tumor accumulations of the pretargeting agent and the radiolabeled effector is independent of tumor size
Our previous studies have indicated that the optimal dosage ratio of pretargeting antibody to effector is proportional to their maximum percent tumor accumulations (MPTAs). This study quantitatively describes how both MPTAs and their ratio change with tumor size, to simplify pretargeting optimizatio...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795388/ https://ncbi.nlm.nih.gov/pubmed/19811906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2009.09.007 |
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