Molecular mechanisms for the persistent bronchodilatory effect of the β(2)-adrenoceptor agonist salmeterol

BACKGROUND: β(2)-adrenoceptor agonists are effective bronchodilators. In vitro studies demonstrated long-lasting airway smooth muscle relaxation by salmeterol after washout, the quick disappearance of this effect in presence of antagonists and its recovery after antagonist removal. Current explanati...

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Bibliographic Details
Main Authors: Szczuka, A, Wennerberg, M, Packeu, A, Vauquelin, G
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
Subjects:
Research Papers with Commentaries
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795256/
https://ncbi.nlm.nih.gov/pubmed/19594756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00296.x
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