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Systemic administration of β(2)-adrenoceptor agonists, formoterol and salmeterol, elicit skeletal muscle hypertrophy in rats at micromolar doses

1. β(2)-Adrenoceptor agonists provide a potential therapy for muscle wasting and weakness, but their use may be limited by adverse effects on the heart, mediated in part, by β(1)-adrenoceptor activation. 2. Two β(2)-agonists, formoterol and salmeterol, are approved for treating asthma and have an ex...

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Bibliografiske detaljer
Main Authors: Ryall, James G, Sillence, Martin N, Lynch, Gordon S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751341/
https://ncbi.nlm.nih.gov/pubmed/16432501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706669
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