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Irbesartan-mediated reduction of renal and cardiac damage in insulin resistant JCR : LA-cp rats

BACKGROUND AND PURPOSE: Angiotensin II receptor antagonists (ARBs), originally developed for antihypertensive properties, have pleiotropic effects including direct vascular actions. We tested the hypothesis that the ARB irbesartan would be effective against micro- and macrovascular complications of...

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Detalhes bibliográficos
Main Authors: Russell, JC, Kelly, SE, Vine, DF, Proctor, SD
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795225/
https://ncbi.nlm.nih.gov/pubmed/19814728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00417.x
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