NS11021, a novel opener of large-conductance Ca(2+)-activated K(+) channels, enhances erectile responses in rats

BACKGROUND AND PURPOSE: Large-conductance Ca(2+)-activated K(+) channels (BK(Ca)), located on the arterial and corporal smooth muscle, are potential targets for treatment of erectile dysfunction (ED). This study investigated whether NS11021 (1-(3,5-Bis-trifluoromethyl-phenyl)-3-[4-bromo-2-(1H-tetraz...

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Hlavní autoři: Kun, A, Matchkov, VV, Stankevicius, E, Nardi, A, Hughes, AD, Kirkeby, HJ, Demnitz, J, Simonsen, U
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2009
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795213/
https://ncbi.nlm.nih.gov/pubmed/19845682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00404.x
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