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DNA damage response to the Mdm2 inhibitor Nutlin-3
Mdm2 inhibitors represent a promising class of p53 activating compounds that may be useful in cancer treatment and prevention. However, the consequences of pharmacological p53 activation are not entirely clear. We observed that Nutlin-3 triggered a DNA damage response in azoxymethane-induced mouse A...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794967/ https://ncbi.nlm.nih.gov/pubmed/19788889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.09.020 |
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