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Small Interfering RNA-mediated CXCR1 or CXCR2 Knock-Down Inhibits Melanoma Tumor Growth and Invasion

CXCR1 and CXCR2 are receptors for CXCL-8 and are differentially expressed on melanoma and endothelial cells. In this study, we determined the functional role of these receptors in melanoma progression. We stably knock-down the expression of CXCR1 and/or CXCR2 in A375-SM (SM; high metastatic) human m...

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Bibliografiska uppgifter
Huvudupphovsmän: Singh, Seema, Sadanandam, Anguraj, Varney, Michelle L., Nannuru, Kalyan C., Singh, Rakesh K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794956/
https://ncbi.nlm.nih.gov/pubmed/19585580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24714
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