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Small Interfering RNA-mediated CXCR1 or CXCR2 Knock-Down Inhibits Melanoma Tumor Growth and Invasion
CXCR1 and CXCR2 are receptors for CXCL-8 and are differentially expressed on melanoma and endothelial cells. In this study, we determined the functional role of these receptors in melanoma progression. We stably knock-down the expression of CXCR1 and/or CXCR2 in A375-SM (SM; high metastatic) human m...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794956/ https://ncbi.nlm.nih.gov/pubmed/19585580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24714 |
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