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Effects of Estradiol on Learned Helplessness and Associated Remodeling of Hippocampal Spine Synapses in Female Rats

BACKGROUND: Despite the fact that women are twice as likely to develop depression as men, our understanding of depression neurobiology in females is limited. We have recently reported in male rats that development of helpless behavior is associated with a severe loss of hippocampal spine synapses, w...

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Detalhes bibliográficos
Main Authors: Hajszan, Tibor, Szigeti-Buck, Klara, Sallam, Nermin L, Bober, Jeremy, Parducz, Arpad, MacLusky, Neil J, Leranth, Csaba, Duman, Ronald S
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794927/
https://ncbi.nlm.nih.gov/pubmed/19811775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.08.017
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