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Remodeling of Hippocampal Spine Synapses in the Rat Learned Helplessness Model of Depression
BACKGROUND: Although it has been postulated for many years that depression is associated with loss of synapses, primarily in the hippocampus, and that antidepressants facilitate synapse growth, we still lack ultrastructural evidence that changes in depressive behavior are indeed correlated with stru...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663388/ https://ncbi.nlm.nih.gov/pubmed/19006787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.09.031 |
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