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Impaired TNF-α Control of IP(3)R-mediated Ca(2+) Release in Alzheimer's Disease Mouse Neurons
The misguided control of inflammatory signaling has been previously implicated in the pathogenesis of several neurological disorders, including Alzheimer's disease (AD). Induction of tumor necrosis factor-alpha (TNF-α), a central mediator of neuroinflammation, occurs commensurate with the onset...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794907/ https://ncbi.nlm.nih.gov/pubmed/19922794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.11.006 |
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