Alternative transcription and splicing of the human porphobilinogen deaminase gene result either in tissue-specific or in housekeeping expression.

Porphobilinogen deaminase [PBGD; porphobilinogen ammonia-lyase (polymerizing), EC 4.3.1.8] is a cytosolic enzyme involved in the heme biosynthetic pathway. Two isoforms of PBGD, encoded by two mRNAs differing solely in their 5' end, are known: one is found in all cells and the other is present...

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Bibliografiska uppgifter
Huvudupphovsmän: Chretien, S, Dubart, A, Beaupain, D, Raich, N, Grandchamp, B, Rosa, J, Goossens, M, Romeo, P H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1988
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC279470/
https://ncbi.nlm.nih.gov/pubmed/3422427
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