MiR-24 Tumor Suppressor Activity Is Regulated Independent of p53 and through a Target Site Polymorphism

MicroRNAs (miRNAs) are predicted to regulate approximately 30% of all human genes; however, only a few miRNAs have been assigned their targets and specific functions. Here we demonstrate that miR-24, a ubiquitously expressed miRNA, has an anti-proliferative effect independent of p53 function. Cell l...

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Bibliografski detalji
Glavni autori: Mishra, Prasun J., Song, Bo, Mishra, Pravin J., Wang, Yuan, Humeniuk, Rita, Banerjee, Debabrata, Merlino, Glenn, Ju, Jingfang, Bertino, Joseph R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794546/
https://ncbi.nlm.nih.gov/pubmed/20041160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008445
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