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Albumin-Binding and Tumor Vasculature Determine the Antitumor Effect of 15-Deoxy-Δ(12,14)-Prostaglandin-J(2) in vivo
15-Deoxy-Δ(12,14)-prostaglandin-J(2) (15d-PGJ(2)), a peroxisome proliferator-activated receptor γ (PPARγ) agonist, induces cell death in tumor cells in vitro; however, no study showed its in vivo effect on tumors. Here, we report that 15d-PGJ(2) shows antitumor effects in vivo in mice. However, its...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Neoplasia Press Inc.
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794516/ https://ncbi.nlm.nih.gov/pubmed/20019843 |
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